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タイトル: | 複雑性尿路感染症におけるFosfomycin Naの使用経験 |
その他のタイトル: | CLIINICAL EXPERIENCE WITH FOSFOMYCIN IN TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS |
著者: | 小松原, 秀一 ![]() 峰山, 浩忠 ![]() 阿部, 礼男 ![]() 小林, 良彦 ![]() |
著者名の別形: | Komatsubara, Shuichi Mineyama, Hirotada Abe, Norio Kobayashi, Yoshihiko |
発行日: | Nov-1981 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 27 |
号: | 11 |
開始ページ: | 1465 |
終了ページ: | 1471 |
抄録: | Seventeen patients with complicated urinary tract infections were administered 4g of fosfomycin sodium by intravenous drip infusion for 90 min twice a day (morning and evening) for 5 days. The results were as follows. 1. In 14 patients for whom global clinical assessment based on " Criteria for Drug Efficacy Evaluation in UTI" was possible, the efficacy was excellent in one, good in 9 and poor in 4, giving an overall efficacy rate of 71% . 2. There were no objective adverse reactions in any of the patients, but a rise in transaminase values thought to be related to the fosfomycin administration was seen in 3 patients. Of these, 2 soon returned to normal, and the condition could not be followed up in one. 3. After the intravenous infusion, the mean drug concentration in the serum peaked at 222.0±39.0 fig/ml, and then decreased rapidly as it was excreted in the urine. |
URI: | http://hdl.handle.net/2433/123228 |
出現コレクション: | Vol.27 No.11 |
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