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Title: 前立腺に発症したGranulocytic Sarcoma(顆粒球性肉腫)の1例
Other Titles: Granulocytic Sarcoma of the Prostate
Authors: 新田, 正広  KAKEN_name
星, 昭夫  KAKEN_name
篠崎, 哲男  KAKEN_name
添田, 宗市  KAKEN_name
川上, 正能  KAKEN_name
金, 伯士  KAKEN_name
中島, 信幸  KAKEN_name
花井, 一也  KAKEN_name
加藤, 成一  KAKEN_name
野本, 剛史  KAKEN_name
臼井, 幸男  KAKEN_name
寺地, 敏郎  KAKEN_name
Author's alias: Nitta, Masahiro
Hoshi, Akio
Shinozaki, Tetsuo
Soeda, Syuichi
Kawakami, Masayoshi
Kin, Hakushi
Nakajima, Nobuyuki
Hanai, Kazuya
Kato, Seiichi
Nomoto, Takeshi
Usui, Yukio
Terachi, Toshiro
Keywords: Granulocytic sarcoma
Acute myeloid leukemia
Issue Date: Sep-2010
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 56
Issue: 9
Start page: 521
End page: 525
Abstract: A 71-year-old man with dysuria was referred to our hospital. The level of serum prostate specific antigen was slightly elevated (4.66 ng/ml), and digital rectal examination revealed a stony hard prostate mass. We performed a transrectal prostate biopsy because malignancy was suspected. Histological examination revealed leukemia-like cells, and bone-marrow examination (aspiration) was performed to determine the location of the original lesion. However, no leukemia-like cells or any other form of malignant cells were identified. Clinical imaging confirmed the absence of any other lesions, and granulocytic sarcoma of the prostate was subsequently diagnosed. We treated the cancer with radiotherapy at a dose of 40 Gy and dysuria improved. Furthermore, significant reduction in prostate volume was confirmed. Four months after initial presentation, the patient developed acute myeloid leukemia [M2 by French-American-British classification]. Induction chemotherapy was initiated, and the patient was successfully induced to complete remission. Twenty months later, the patient showed relapse. Despite salvage chemotherapy, he died of brain hemorrhage twenty-four months after complete remission.
Rights: 許諾条件により本文は2011-10-01に公開
PubMed ID: 20940529
Appears in Collections:Vol.56 No.9

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