ネパール高所住民の胃十二指腸病変

Abstract

標高3, 000m以上に居住するネパールクンブ地方の高所住民56名, 並びに対照群としてカトマンズ在住の45名に対し胃内視鏡検査を行ない高所環境下に於ける胃十二指腸病変の比較検討を行った. 胃十二指腸病変はクンブ地方36%(20/56), カトマンス20%(9/45)とクンブ地方に多く認められ, 特に消化性潰蕩がクンブ地方に好発していた(16%対7%). 以上により高所環境では消化性潰蕩をはじめとする胃十二指腸病変が発生しやすい傾向にあることが確認できた.

Endoscopic examination was conducted on 56 Nepalese highlanders to evaluate exact condition of gastro-duodenal mucosa at high altitude. As control, 45 lowlanders had also the same examination at sea level. 20 of 56 (36%) high landers, including 9 (16%) cases of peptic ulcer, had gastro-duodenal lesions. On the other hand, 9 of 45 (20%) low landers, had some gastro-duodenal lesions among which 3 (7%) cases were peptic ulcers. These data indicate that gastro-duodenal mucosa may be damaged easily at high altitude.