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dc.contributor.author水野, 桂ja
dc.contributor.author井上, 貴博ja
dc.contributor.author宮崎, 有ja
dc.contributor.author牧野, 雄樹ja
dc.contributor.author寺田, 直樹ja
dc.contributor.author小林, 恭ja
dc.contributor.author山﨑, 俊成ja
dc.contributor.author松井, 喜之ja
dc.contributor.author神波, 大己ja
dc.contributor.author吉村, 耕治ja
dc.contributor.author三上, 芳喜ja
dc.contributor.author小川, 修ja
dc.contributor.alternativeMizuno, Keien
dc.contributor.alternativeInoue, Takahiroen
dc.contributor.alternativeMiyazaki, Yuen
dc.contributor.alternativeMakino, Yukien
dc.contributor.alternativeTerada, Naokien
dc.contributor.alternativeKobayashi, Takashien
dc.contributor.alternativeYamasaki, Toshinarien
dc.contributor.alternativeMatsui, Yoshiyukien
dc.contributor.alternativeKamba, Tomomien
dc.contributor.alternativeYoshimura, Kojien
dc.contributor.alternativeMikami, Yoshikien
dc.contributor.alternativeOgawa, Osamuen
dc.date.accessioned2014-12-17T01:03:27Z-
dc.date.available2014-12-17T01:03:27Z-
dc.date.issued2014-11-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/192328-
dc.description.abstractNeurovascular bundle (NVB) preservation is a mandatory procedure to maintain erectile function of localized prostate cancer patients after radical prostatectomy (RP). However, in terms of cancer control, indications to select appropriate patients for nerve-sparing RP are still controversial. In this study, we examined the pathological findings of RP specimens to develop a preoperative criterion for NVB preservation during RP. The study included 76 patients who underwent RP at our institution from 2006 to 2008, and we retrospectively analyzed RP specimens pathologically. The distance between NVB and foci of prostate cancer was measured in 135 prostate sides, and preoperative factors which predict the distance of ≤2 mm was evaluated. Univariate analysis showed that side-specific positive biopsy core rate ≥33.3%, sidespecific maximum tumor length in biopsy core ≥5 mm and side-specific tumor involvement rate in biopsy core ≥50% was associated with the risk of the distance of ≤2 mm. Multivariate analysis revealed that sidespecific positive biopsy core rate ≥33.3% was the only significant predictor of the ipsilateral NVB-tumor distance ≤2 mm (p=0.0055, odds ratio 3.49). Based on this study, a nerve-sparing criterion of <33.3% side-specific percent positive biopsy core was developed at our institution. Prospective data on patients who were applied this criterion are needed to evaluate its clinical safety and feasibility.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.rights許諾条件により本文は2015/12/01に公開ja
dc.subjectRadical Prostatectomyen
dc.subjectNerve-sparingen
dc.subject.ndc494.9-
dc.title京都大学病院での前立腺全摘術における神経温存適応基準構築に関する検討ja
dc.title.alternativeDevelopment of a Preoperative Criterion to Select Candidates for Nerve-Sparing Radical Prostatectomy at Kyoto University Hospitalen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume60-
dc.identifier.issue11-
dc.identifier.spage543-
dc.identifier.epage547-
dc.textversionpublisher-
dc.sortkey03-
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部泌尿器科ja
dc.address京都大学医学部病理診断科ja
dc.address京都大学医学部泌尿器科ja
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.address.alternativeThe Department of Diagnostic Pathology, Kyoto University School of Medical Scienceen
dc.address.alternativeThe Department of Urology, Kyoto University Graduate School of Medicineen
dc.identifier.pmid25511940-
dcterms.accessRightsopen access-
datacite.date.available2015-12-01-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol. 60 No. 11

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