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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.tet.2015.05.006.pdf | 274.01 kB | Adobe PDF | 見る/開く |
| タイトル: | Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides |
| 著者: | Iwata, Akira Inuki, Shinsuke    https://orcid.org/0000-0002-7525-1280 (unconfirmed)Oishi, Shinya https://orcid.org/0000-0002-2833-2539 (unconfirmed)Fujii, Nobutaka Ohno, Hiroaki https://orcid.org/0000-0002-3246-4809 (unconfirmed) |
| 著者名の別形: | 藤井, 信孝 大野, 浩章 |
| キーワード: | Palladium Spiroindole Cascade cyclization Catalytic asymmetric reaction |
| 発行日: | Sep-2015 |
| 出版者: | Elsevier Ltd. |
| 誌名: | Tetrahedron |
| 巻: | 71 |
| 号: | 37 |
| 開始ページ: | 6580 |
| 終了ページ: | 6585 |
| 抄録: | Herein, we report the palladium-catalyzed cyclization reactions of indoles bearing a propargyl chloride side chain at their 3-position. In the presence of an external nucleophile, such as a sulfonamide or malonate, indoles bearing a propargyl group at their 3-position gave fused tetracyclic spiroindolines preferentially. However, in the absence of an external nucleophile, the same substrates afforded spiroindoles. Our attempts to develop a catalytic asymmetric spirocyclization onto a propargylpalladium species are also presented in this paper. |
| 記述: | Available online 9 May 2015 |
| 著作権等: | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ The full-text file will be made open to the public on 9 May 2017 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| URI: | http://hdl.handle.net/2433/202050 |
| DOI(出版社版): | 10.1016/j.tet.2015.05.006 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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