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acs.joc.0c00238.pdf | correction | 64.78 kB | Adobe PDF | 見る/開く |
タイトル: | Construction of the Pyrrolo[2,3- d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide |
著者: | Matsuoka, Junpei Kumagai, Hiroshi Inuki, Shinsuke https://orcid.org/0000-0002-7525-1280 (unconfirmed) Oishi, Shinya Ohno, Hiroaki https://orcid.org/0000-0002-3246-4809 (unconfirmed) |
著者名の別形: | 松岡, 純平 井貫, 晋輔 大石, 真也 大野, 浩章 |
発行日: | 19-Jul-2019 |
出版者: | American Chemical Society |
誌名: | Journal of Organic Chemistry |
巻: | 84 |
号: | 14 |
開始ページ: | 9358 |
終了ページ: | 9363 |
抄録: | We achieved direct construction of the common pyrrolo[2, 3-d]carbazole core of aspidosperma and malagasy alkaloids by a gold-catalyzed cascade cyclization of ynamide. This reaction involves intramolecular cyclization from indole to ynamide followed by trapping of the resulting iminium intermediate. Through the use of chiral gold complexes, an enantiomerically enriched pyrrolo[2, 3-d]carbazole was obtained in up to 74% ee. This methodology was successfully applied to the asymmetric formal synthesis of vindorosine. |
記述: | ADDITION / CORRECTION This article has been corrected. View the notice : Correction to Construction of the Pyrrolo[2,3-d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide -- https://doi.org/10.1021/acs.joc.0c00238 |
著作権等: | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.joc.9b01149. The full-text file will be made open to the public on 3 June 2020 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/243213 |
DOI(出版社版): | 10.1021/acs.joc.9b01149 |
PubMed ID: | 31244165 |
関連リンク: | https://doi.org/10.1021/acs.joc.0c00238 |
出現コレクション: | 学術雑誌掲載論文等 |
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