脊髄髄膜瘤による神経因性膀胱患者に発症した膀胱扁平上皮癌の1例

Abstract

A 38-year-old woman with neurogenic bladder caused by myelomeningocele, who had been on clean intermittent self-catheterization for years, complained of gross hematuria. Computerized tomography, urinary cytology and cystoscopy failed to reveal causative lesions and the hematuria ceased spontaneously. Because gross hematuria recurred 2 years later, we examined the patient again and detected calcification of the urinary bladder. Mucosal lesions suspicious of bladder tumor were detected during the transurethral surgery for the calcified lesion, and we promptly performed biopsy. As a result, she was diagnosed with invasive bladder squamous cell carcinoma. Radical cystectomy and urinary diversion were performed and the histopathological diagnosis was pT3aN0. Adjuvant therapies were not performed. No recurrence has been observed for 36 months after the surgery.