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タイトル: | Computational neuroanatomy of human stratum proprium of interparietal sulcus |
著者: | Uesaki, Maiko Takemura, Hiromasa Ashida, Hiroshi https://orcid.org/0000-0002-2930-402X (unconfirmed) |
著者名の別形: | 上崎, 麻衣子 蘆田, 宏 |
キーワード: | Stratum proprium of interparietal sulcus Diffusion-weighted MRI Tractography fMRI Optic flow Visuo-vestibular integration |
発行日: | Jan-2018 |
出版者: | Springer Nature |
誌名: | Brain Structure and Function |
巻: | 223 |
号: | 1 |
開始ページ: | 489 |
終了ページ: | 507 |
抄録: | Recent advances in diffusion-weighted MRI (dMRI) and tractography have enabled identification of major long-range white matter tracts in the human brain. Yet, our understanding of shorter tracts, such as those within the parietal lobe, remains limited. Over a century ago, a tract connecting the superior and inferior parts of the parietal cortex was identified in a post-mortem study: stratum proprium of interparietal sulcus (SIPS; Sachs, Das hemisphärenmark des menschlichen grosshirns. Verlag von georg thieme, Leipzig, 1892). The tract has since been replicated in another fibre dissection study (Vergani et al., Cortex 56:145–156, 2014), however, it has not been fully investigated in the living human brain and its precise anatomical properties are yet to be described. We used dMRI and tractography to identify and characterise SIPS in vivo, and explored its spatial proximity to the cortical areas associated with optic-flow processing using fMRI. SIPS was identified bilaterally in all subjects, and its anatomical position and trajectory are consistent with previous post-mortem studies. Subsequent evaluation of the tractography results using the linear fascicle evaluation and virtual lesion analysis yielded strong statistical evidence for SIPS. We also found that the SIPS endpoints are adjacent to the optic-flow selective areas. In sum, we show that SIPS is a short-range tract connecting the superior and inferior parts of the parietal cortex, wrapping around the intraparietal sulcus, and that it may be a crucial anatomy underlying optic-flow processing. In vivo identification and characterisation of SIPS will facilitate further research on SIPS in relation to cortical functions, their development, and diseases that affect them. |
著作権等: | © The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
URI: | http://hdl.handle.net/2433/274013 |
DOI(出版社版): | 10.1007/s00429-017-1492-1 |
PubMed ID: | 28871500 |
出現コレクション: | 学術雑誌掲載論文等 |
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