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Title: イピリムマブ・ニボルマブ併用療法が著効した乳頭状腎細胞癌の1例
Other Titles: A Case of Pappilary Renal Cell Caircinoma which Responded Well to the Combination Therapy of Ipilimumab and Nivolumab --A CASE REPORT--
Authors: 深谷, 友祐  KAKEN_name
大豆本, 圭  KAKEN_name
角陸, 文哉  KAKEN_name
山本, 拓  KAKEN_name
佐々木, 雄太郎  KAKEN_name
尾崎, 啓介  KAKEN_name
上野, 恵輝  KAKEN_name
津田, 恵  KAKEN_name
楠原, 義人  KAKEN_name
布川, 朋也  KAKEN_name
山本, 恭代  KAKEN_name
山口, 邦久  KAKEN_name
高橋, 正幸  KAKEN_name
金山, 博臣  KAKEN_name
仁木, 真理子  KAKEN_name
上原, 久典  KAKEN_name
Author's alias: FUKATANI, Yusuke
DAIZUMOTO, Kei
KADORIKU, Fumiya
YAMAMOTO, Hiraku
SASAKI, Yutaro
OZAKI, Keisuke
UENO, Yoshiteru
TUDA, Megumi
KUSUHARA, Yoshito
FUKAWA, Tomoya
YAMAMOTO, Yasuyo
YAMAGUCHI, Kunihisa
TAKAHASHI, Masayuki
KANAYAMA, Hiroomi
NIKI, Mariko
UEHARA, Hisanori
Keywords: Papillary renal cell carcinoma
Ipilimumab and nivolumab
Issue Date: 30-Apr-2022
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 68
Issue: 4
Start page: 107
End page: 111
Abstract: We report a case of papillary renal cell carcinoma that responded well to the combination of ipilimumab and nivolumab. The patient was a 68-year-old male who was being followed up for a small left renal mass without treatment. Two years later, computed tomography (CT) showed enlarged cervical and para-aortic lymph nodes, and lymph node biopsy suggested metastases of the cancer. After resection of the renal tumor, we performed pararenal aortic lymph node biopsy, and we diagnosed the case as papillary renal cell carcinoma type 1 with lymph node metastasis. The combination of ipilimumab and nivolumab each metastatic site showed regression on CT. Since immune-related adverse events occurred during the therapy nivolumab was discontinued, but partial response of the metastases was maintained.
Rights: 許諾条件により本文は2023/05/01に公開
DOI: 10.14989/ActaUrolJap_68_4_107
URI: http://hdl.handle.net/2433/274083
PubMed ID: 35613898
Appears in Collections:Vol.68 No.4

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