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Title: Development of biomass waste-based carbon quantum dots and their potential application as non-toxic bioimaging agents
Authors: Abu, Norhidayah
Chinnathambi, Shanmugavel  kyouindb  KAKEN_id  orcid (unconfirmed)
Kumar, Mahima
Etezadi, Fatemeh
Bakhori, Noremylia Mohd
Zubir, Zuhana Ahmad
Md Salleh, Shahrul Nizam
Shueb, Rafidah Hanim
Karthikeyan, Subramani
Thangavel, Vaijayanthi
Abdullah, Jaafar
Pandian, Ganesh N.
Issue Date: 25-Sep-2023
Publisher: Royal Society of Chemistry (RSC)
Journal title: RSC Advances
Volume: 13
Issue: 40
Start page: 28230
End page: 28249
Abstract: Over recent years, carbon quantum dots (CQDs) have advanced significantly and gained substantial attention for their numerous benefits. These benefits include their simple preparation, cost-effectiveness, small size, biocompatibility, bright luminescence, and low cytotoxicity. As a result, they hold great potential for various fields, including bioimaging. A fascinating aspect of synthesizing CQDs is that it can be accomplished by using biomass waste as the precursor. Furthermore, the synthesis approach allows for control over the physicochemical characteristics. This paper unequivocally examines the production of CQDs from biomass waste and their indispensable application in bioimaging. The synthesis process involves a simple one-pot hydrothermal method that utilizes biomass waste as a carbon source, eliminating the need for expensive and toxic reagents. The resulting CQDs exhibit tunable fluorescence and excellent biocompatibility, making them suitable for bioimaging applications. The successful application of biomass-derived CQDs has been demonstrated through biological evaluation studies in various cell lines, including HeLa, Cardiomyocyte, and iPS, as well as in medaka fish eggs and larvae. Using biomass waste as a precursor for CQDs synthesis provides an environmentally friendly and sustainable alternative to traditional methods. The resulting CQDs have potential applications in various fields, including bioimaging.
Rights: © 2023 The Author(s). Published by the Royal Society of Chemistry
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
DOI(Published Version): 10.1039/d3ra05840a
PubMed ID: 37753403
Appears in Collections:Journal Articles

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