ペルテス病について--同胞に発症し兄が白血病を合併した2症例--

Abstract

Perthes' disease is generally considered to represent an avascular necrosis of the proximal femoral epiphysis. However, the cause of this impairment of blood supply is unknown. Some hypotheses about trauma, synovitis, or vascular occlusion are implicated. We report two cases of Perthes' disease herein. The patients are siblings. They are treated with Tachdjian abduction brace successfully. The elder brother developed leukemia, and the bone marrow was transplanted from the younger brother. The HLA (human leukocyte antigen) typing of his family is reported and discussed. It is argued about the transient synovitis of the hip in children and its possible role in the development of Perthes' disease.