<原著>BAY b 5097 の経気管支注入の経験 : 肺 Aspergilloma の 1 例

Abstract

A case diagnosed as intrapulmonary aspergilloma on the basis of sputum culture, bronchial secretion culture, and chest X rays, was treated with BAY b 5097 orally and by perbronchial infusion. The case became negative for fungus ball for some time. The suspension consisted of 1 mg/ml BAY b 5097 in a mixture in equal volumes of glycerin and physiological saline solution was infused by means of Metras catheter at the segmental bronchus under fluoroscopic television. The infusion was performed twice within 3 weeks, with a total of 60 mg BAY b 5097. The fungus ball disappeared for some time but seems to have reappeared. Perbronchial infusion of BAY b 5097 could likely be of value, as an adjunct in the chemotherapy of intrapulmonary aspergillomas, if further investigations have established adequate dosage and frequency of administration.