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Title: 無精子症における染色体異常の検討
Other Titles: Chromosomal investigation in infertile cases of azoospermia
Authors: 堀, 夏樹  KAKEN_name
山本, 逸夫  KAKEN_name
林, 宣男  KAKEN_name
杉村, 芳樹  KAKEN_name
鈴木, 泉  KAKEN_name
桜井, 正樹  KAKEN_name
荒木, 富雄  KAKEN_name
塚本, 勝己  KAKEN_name
山川, 謙輔  KAKEN_name
川村, 寿一  KAKEN_name
Author's alias: HORI, Natsuki
YAMAMOTO, Itsuo
HAYASHI, Norio
SUGIMURA, Yoshiki
SUZUKI, Sen
SAKURAI, Masaki
ARAKI, Tomio
TSUKAMOTO, Katsumi
YAMAKAWA, Kensuke
KAWAMURA, Juichi
Keywords: Azoospermia
Chromosomal abnormality
XX-male
Klinefelter's syndrome
Issue Date: Feb-1987
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 33
Issue: 2
Start page: 187
End page: 192
Abstract: 無精子症85例に対し末梢血リンパ球培養による染色体検査を施行したところ,23例(27%)になんらかの異常をみとめた.最も多くみられたのが47,XXYのクラインフェルター症候群の17例であった.希有な疾患として46,XXp+ (XX maleとしては本邦30例目,XXp+としては2例目),46,XYp+(既報告なし),46,XYq- (7例目)などを認めた.常染色体異常としては,転座2例,r(18)が1例であった
Chromosomal examination in 85 patients with azoospermia revealed 62 patients (73%) with the karyotype 46, XY and 23 patients (27%) with other abnormal karyotypes. In this population, there were 17 patients with 47, XXY. Other anomalies were: 46, XYp+, 46, XXp+, 46, XYp-, 45, X, t (Ynf; 21), 45, XY, t (13q 15q), and 46, XY, r (18). Serum LH and FSH levels were high and testosterone level was low in the patients with 47, XXY compared with the other 6 patients (p less than 0.01). Also the mean value of testicular volume was low in the patients with 47, XXY (p less than 0.05).
URI: http://hdl.handle.net/2433/119053
PubMed ID: 3109223
Appears in Collections:Vol.33 No.2

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