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Title: 尿路感染症に対するCephalexinの応用
Other Titles: Cephalexin for urinary tract infection
Authors: 石神, 襄次  KAKEN_name
原, 信二  KAKEN_name
三田, 俊彦  KAKEN_name
Author's alias: Ishigami, Joji
Hara, Shinji
Mita, Toshihiko
Keywords: Adolescent
Bacteria/drug effects
Cephalosporins/adverse effects/blood/pharmacology/therapeutic use/urine
Child, Preschool
Middle Aged
Urinary Tract Infections/drug therapy
Issue Date: Jul-1969
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 15
Issue: 7
Start page: 522
End page: 530
Abstract: 1) Clinical results. CEPHALEXIN (CEX) was orally administered to fifty cases of urinary tract infection. Clinical result was as follows: excellent 35, fair 7 and non-effective 8. The effectiveness was, therefore, estimated to be 84%. 2) Blood levels. The highest blood level after single administration of 0.5 or 1.0 gram of CEX was observed at one hour. Then, the blood level fell rapidly, although the effective level continued to four hours. 3) Urinary excretion. Eighty percent of CEX of 1.0 g in a single dosage was proved to be excreted in urine in six hours. 4) Antimicrobial potency. Approximately 1/2 to 1/4 of antimicrobial potency of CER was observed against Staphylococcus, E. coli, Proteus and Klebsiella. 5) Side effects. No side effect worthy to mention was observed.
PubMed ID: 5388484
Appears in Collections:Vol.15 No.7

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