ダウンロード数: 257
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
29_0017.pdf | 358.1 kB | Adobe PDF | 見る/開く |
タイトル: | 泌尿器科領域の悪性腫瘍における血清ferritinの検討(第2報) |
その他のタイトル: | Clinical evaluation of serum ferritin levels in urologic cancer (II) |
著者: | 和志田, 裕人 伏見, 登 津ヶ谷, 正行 |
著者名の別形: | Washida, Hiroto Fushimi, Noboru Tsugaya, Masayuki |
キーワード: | Adult Female Ferritins/blood Humans Kidney Neoplasms/blood/diagnosis Male Middle Aged Prostatic Neoplasms/blood/diagnosis Radioimmunoassay Urinary Bladder Neoplasms/blood/diagnosis |
発行日: | Jan-1983 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 29 |
号: | 1 |
開始ページ: | 17 |
終了ページ: | 22 |
抄録: | 泌尿器科悪性腫瘍患者を対象に, 血清ferritinをSPAC, RIA-Gnostにより測定し, tumor markerとしての意義を検討した.RIA-Gnostにおける正常男子の血清ferritin値は, 142.5±67.5 ng/ml (n=58), 正常女子は49.6±28.8 ng/ml (n=76)であった.膀胱癌患者22例の血清ferritin値は, 両測定法において正常よりやや低値を示し, 陽性率はそれぞれ30%前後であった.前立腺癌患者22例においては, 両測定法とも陽性率は45.5%であり, RIA-Gnostにおいては, 前立腺癌患者の血清ferritin値は高く, 正常男子との間にP<0.1%で有意差を認めた.腎癌患者6例の血清ferritin値は, RIA-Gnostにおいて, P<0.1%で有意に高く100%の陽性率であった.SPACにおいては陽性率67%であった.血清ferritinは, とくにRIA-Gnostにおいて腎癌患者のtumor markerとして意義を認めた By means of the RIA-Gnost Ferritin and Spac Ferritin kits, the serum ferritin levels of patients with some urological malignant diseases were quantitated; and, the clinical significance of these values as a tumor marker was discussed. The normal (reference) level in serum obtained by the RIA-Gnost kit was 142.5 +/- 67.5 ng/ml (n = 58) for healthy males and 49.6 +/- 28.8 ng/ml (n = 76) for healthy females. The assay values for 22 cases of bladder cancer by both kits were somewhat lower than the normal range, and the positive rates presented were around 30%, being in rough agreement with each other. The positive rate for 22 patients with prostatic cancer was 45.5% by either method. The assay values obtained by the RIA-Gnost kit was higher and differed significantly (p less than 0.1%) from those obtained on healthy males. Furthermore, the same tendency was found in 6 cases of renal cancer. The assay values of RIA-Gnost were significantly higher (p less than 0.1%) than normal; and, the positive rate was 100% for RIA-Gnost and 67% for Spac . In conclusion, serum ferritin determination especially that by the RIA-Gnost kit proved to be a useful and significant tumor marker for the detection of renal cancer. |
URI: | http://hdl.handle.net/2433/120106 |
PubMed ID: | 6677086 |
出現コレクション: | Vol.29 No.1 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。