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DCフィールド | 値 | 言語 |
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dc.contributor.author | Kinoshita, Masahiro | en |
dc.contributor.alternative | 木下, 正弘 | ja |
dc.date.accessioned | 2014-09-25T07:40:05Z | - |
dc.date.available | 2014-09-25T07:40:05Z | - |
dc.date.issued | 2013-09 | - |
dc.identifier.issn | 1867-2450 | - |
dc.identifier.uri | http://hdl.handle.net/2433/189841 | - |
dc.description.abstract | Upon biological self-assembly, the number of accessible translational configurations of water in the system increases considerably, leading to a large gain in water entropy. It is important to calculate the solvation entropy of a biomolecule with a prescribed structure by accounting for the change in water–water correlations caused by solute insertion. Modeling water as a dielectric continuum is not capable of capturing the physical essence of the water entropy effect. As a reliable tool, we propose a hybrid of the angle-dependent integral equation theory combined with a multipolar water model and a morphometric approach. Using our methods wherein the water entropy effect is treated as the key factor, we can elucidate a variety of processes such as protein folding, cold, pressure, and heat denaturating of a protein, molecular recognition, ordered association of proteins such as amyloid fibril formation, and functioning of ATP-driven proteins. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Springer Berlin Heidelberg | en |
dc.rights | The final publication is available at Springer via http://dx.doi.org/10.1007/s12551-013-0100-8 | en |
dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
dc.rights | This is not the published version. Please cite only the published version. | en |
dc.subject | Solvation entropy | en |
dc.subject | Biological self-assembly | en |
dc.subject | Protein folding | en |
dc.subject | Protein denaturation | en |
dc.subject | Molecular recognition | en |
dc.subject | ATP-driven protein | en |
dc.subject | Integral equation theory | en |
dc.subject | Morphometric approach | en |
dc.title | A new theoretical approach to biological self-assembly | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Biophysical Reviews | en |
dc.identifier.volume | 5 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 283 | - |
dc.identifier.epage | 293 | - |
dc.relation.doi | 10.1007/s12551-013-0100-8 | - |
dc.textversion | author | - |
dc.identifier.pmid | 28510109 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 1867-2450 | - |
dc.identifier.eissn | 1867-2469 | - |
出現コレクション: | 学術雑誌掲載論文等 |
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