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A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2 Kim, Kwang Su; Ejima, Keisuke; Iwanami, Shoya; Fujita, Yasuhisa; Ohashi, Hirofumi; Koizumi, Yoshiki; Asai, Yusuke; Nakaoka, Shinji; Watashi, Koichi; Aihara, Kazuyuki; Thompson, Robin N.; Ke, Ruian; Perelson, Alan S.; Iwami, Shingo (2021-03-22) PLOS Biology, 19(3)
Designing isolation guidelines for COVID-19 patients with rapid antigen tests Jeong, Yong Dam; Ejima, Keisuke; Kim, Kwang Su; Joohyeon, Woo; Iwanami, Shoya; Fujita, Yasuhisa; Jung, Il Hyo; Aihara, Kazuyuki; Shibuya, Kenji; Iwami, Shingo; Bento, Ana I.; Ajelli, Marco (2022) Nature Communications, 13
Revisiting the guidelines for ending isolation for COVID-19 patients Jeong, Yong Dam; Ejima, Keisuke; Kim, Kwang Su; Iwanami, Shoya; Bento, Ana I; Fujita, Yasuhisa; Jung, Il Hyo; Aihara, Kazuyuki; Watashi, Koichi; Miyazaki, Taiga; Wakita, Takaji; Iwami, Shingo; Ajelli, Marco (2021) eLife, 10
Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials: A modeling study Iwanami, Shoya; Ejima, Keisuke; Kim, Kwang Su; Noshita, Koji; Fujita, Yasuhisa; Miyazaki, Taiga; Kohno, Shigeru; Miyazaki, Yoshitsugu; Morimoto, Shimpei; Nakaoka, Shinji; Koizumi, Yoshiki; Asai, Yusuke; Aihara, Kazuyuki; Watashi, Koichi; Thompson, Robin N.; Shibuya, Kenji; Fujiu, Katsuhito; Perelson, Alan S.; Iwami, Shingo; Wakita, Takaji (2021-07) PLOS Medicine, 18(7)
Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma Iwanami, Shoya; Kitagawa, Kosaku; Ohashi, Hirofumi; Asai, Yusuke; Shionoya, Kaho; Saso, Wakana; Nishioka, Kazane; Inaba, Hisashi; Nakaoka, Shinji; Wakita, Takaji; Diekmann, Odo; Iwami, Shingo; Watashi, Koichi (2020-07-30) PLOS Biology, 18(7)
Analysis of the risk and pre-emptive control of viral outbreaks accounting for within-host dynamics: SARS-CoV-2 as a case study Hart, William S.; Park, Hyeongki; Jeong, Yong Dam; Kim, Kwang Su; Yoshimura, Raiki; Thompson, Robin N.; Iwami, Shingo (2023-10-10) Proceedings of the National Academy of Sciences of the United States of America, 120(41)
Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection Miyamoto, Sho; Nishiyama, Takara; Ueno, Akira; Park, Hyeongki; Kanno, Takayuki; Nakamura, Naotoshi; Ozono, Seiya; Aihara, Kazuyuki; Takahashi, Kenichiro; Tsuchihashi, Yuuki; Ishikane, Masahiro; Arashiro, Takeshi; Saito, Shinji; Ainai, Akira; Hirata, Yuichiro; Iida, Shun; Katano, Harutaka; Tobiume, Minoru; Tokunaga, Kenzo; Fujimoto, Tsuguto; Suzuki, Michiyo; Nagashima, Maki; Nakagawa, Hidenori; Narita, Masashi; Kato, Yasuyuki; Igari, Hidetoshi; Fujita, Kaori; Kato, Tatsuo; Hiyama, Kazutoshi; Shindou, Keisuke; Adachi, Takuya; Fukushima, Kazuaki; Nakamura-Uchiyama, Fukumi; Hase, Ryota; Yoshimura, Yukihiro; Yamato, Masaya; Nozaki, Yasuhiro; Ohmagari, Norio; Suzuki, Motoi; Saito, Tomoya; Iwami, Shingo; Suzuki, Tadaki (2023-12-26) Proceedings of the National Academy of Sciences of the United States of America, 120(52)
Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution Sunagawa, Junya; Park, Hyeongki; Kim, Kwang Su; Komorizono, Ryo; Choi, Sooyoun; Ramirez Torres, Lucia; Woo, Joohyeon; Jeong, Yong Dam; Hart, William S.; Thompson, Robin N.; Aihara, Kazuyuki; Iwami, Shingo; Yamaguchi, Ryo (2023-11-21) Nature Communications, 14