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BibliographyContents
Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities.
  Hanaki, Yusuke; Yanagita, Ryo C; Sugahara, Takahiro; Aida, Misako; Tokuda, Harukuni; Suzuki, Nobutaka; Irie, Kazuhiro (2015)
  Bioscience, biotechnology, and biochemistry, 79(6): 888-895
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Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.
  Irie, Kazuhiro; Yanagita, Ryo C (2014-04)
  The Chemical Record, 14(2): 251-267
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Synthesis and structure–activity studies of simplified analogues of aplysiatoxin with antiproliferative activity like bryostatin-1
  Irie, Kazuhiro; Kikumori, Masayuki; Kamachi, Hiroaki; Tanaka, Keisuke; Murakami, Akira; Yanagita, Ryo C.; Tokuda, Harukuni; Suzuki, Nobutaka; Nagai, Hiroshi; Suenaga, Kiyotake; Nakagawa, Yu (2012)
  Pure and Applied Chemistry, 84(6): 1341-1351
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Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin
  NAKAGAWA, Yu; KIKUMORI, Masayuki; YANAGITA, Ryo C.; MURAKAMI, Akira; TOKUDA, Harukuni; NAGAI, Hiroshi; IRIE, Kazuhiro (2011-06)
  Bioscience, Biotechnology, and Biochemistry, 75(6): 1167-1173
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Identification and Biological Activities of Bryostatins from Japanese Bryozoan
  UENO, Sayo; YANAGITA, Ryo C.; MURAKAMI, Kazuma; MURAKAMI, Akira; TOKUDA, Harukuni; SUZUKI, Nobutaka; FUJIWARA, Takeshi; IRIE, Kazuhiro (2012-05)
  Bioscience, Biotechnology, and Biochemistry, 76(5): 1041-1043
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Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities
  Hanaki, Yusuke; Kikumori, Masayuki; Tokuda, Harukuni; Okamura, Mutsumi; Dan, Shingo; Adachi, Naoko; Saito, Naoaki; Yanagita, Ryo C.; Irie, Kazuhiro (2017-04-13)
  Molecules, 22(4)
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New diagnostic method for Alzheimer’s disease based on the toxic conformation theory of amyloid β
  Irie, Kazuhiro (2020)
  Bioscience, Biotechnology and Biochemistry, 84(1): 1-16
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