ブラウズ : 著者 00168535
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Asymmetric Total Synthesis of Shagenes A and B Tsukano, Chihiro; Yagita, Ryotaro; Heike, Takayoshi; Mohammed, Tagwa A.; Nishibayashi, Kazuya; Irie, Kazuhiro; Takemoto, Yoshiji (2021-10) Angewandte Chemie International Edition, 60(43): 23106-23111 | |
Identification and Biological Activities of Bryostatins from Japanese Bryozoan UENO, Sayo; YANAGITA, Ryo C.; MURAKAMI, Kazuma; MURAKAMI, Akira; TOKUDA, Harukuni; SUZUKI, Nobutaka; FUJIWARA, Takeshi; IRIE, Kazuhiro (2012-05) Bioscience, Biotechnology, and Biochemistry, 76(5): 1041-1043 | |
Improved and large-scale synthesis of 10-methyl-aplog-1, a potential lead for an anticancer drug Kikumori, Masayuki; Yanagita, Ryo C.; Irie, Kazuhiro (2014-12) Tetrahedron, 70(52): 9776-9782 | |
Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis) Izumi, Yasuhiko; Matsumura, Atsuko; Wakita, Seiko; Akagi, Ken-Ichi; Fukuda, Hiroyuki; Kume, Toshiaki; Irie, Kazuhiro; Takada-Takatori, Yuki; Sugimoto, Hachiro; Hashimoto, Tadashi; Akaike, Akinori (2012-06-27) Free radical biology & medicine, 53(4): 669-679 | |
Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities Hanaki, Yusuke; Kikumori, Masayuki; Tokuda, Harukuni; Okamura, Mutsumi; Dan, Shingo; Adachi, Naoko; Saito, Naoaki; Yanagita, Ryo C.; Irie, Kazuhiro (2017-04-13) Molecules, 22(4) | |
Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer's disease diagnosis. Murakami, Kazuma; Tokuda, Maki; Suzuki, Takashi; Irie, Yumi; Hanaki, Mizuho; Izuo, Naotaka; Monobe, Yoko; Akagi, Ken-Ichi; Ishii, Ryotaro; Tatebe, Harutsugu; Tokuda, Takahiko; Maeda, Masahiro; Kume, Toshiaki; Shimizu, Takahiko; Irie, Kazuhiro (2016-07-04) Scientific reports, 6 | |
New diagnostic method for Alzheimer’s disease based on the toxic conformation theory of amyloid β Irie, Kazuhiro (2020) Bioscience, Biotechnology and Biochemistry, 84(1): 1-16 | |
Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1 Igarashi, Yoko; Ohnishi, Kohta; Irie, Kazuhiro; Murakami, Akira (2016-08-18) PLOS ONE, 11(8) | |
An RNA aptamer with potent affinity for a toxic dimer of amyloid β42 has potential utility for histochemical studies of Alzheimer's disease Murakami, Kazuma; Obata, Yayoi; Sekikawa, Asa; Ueda, Haruka; Izuo, Naotaka; Awano, Tatsuya; Takabe, Keiji; Shimizu, Takahiko; Irie, Kazuhiro (2020-04-10) Journal of Biological Chemistry, 295(15): 4870-4880 | |
Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity. Yanagita, Ryo C; Kamachi, Hiroaki; Tanaka, Keisuke; Murakami, Akira; Nakagawa, Yu; Tokuda, Harukuni; Nagai, Hiroshi; Irie, Kazuhiro (2010-10-15) Bioorganic & medicinal chemistry letters, 20(20): 6064-6066 | |
Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues. Sato, Mizuho; Murakami, Kazuma; Uno, Mayumi; Nakagawa, Yu; Katayama, Sumie; Akagi, Ken-ichi; Masuda, Yuichi; Takegoshi, Kiyonori; Irie, Kazuhiro (2013-08-09) The Journal of biological chemistry, 288(32): 23212-23224 | |
Soybean extracts increase cell surface ZIP4 abundance and cellular zinc levels: A potential novel strategy to enhance zinc absorption by ZIP4 targeting Hashimoto, Ayako; Ohkura, Katsuma; Takahashi, Masakazu; Kizu, Kumiko; Narita, Hiroshi; Enomoto, Shuichi; Miyamae, Yusaku; Masuda, Seiji; Nagao, Masaya; Irie, Kazuhiro; Ohigashi, Hajime; Andrews, Glen K.; Kambe, Taiho (2015-12) Biochemical Journal, 472(2): 183-193 | |
Studies Toward the Total Synthesis of Schinortriterpenoids: Diastereoselective Synthesis of the Left‐Hand Fragment Yagita, Ryotaro; Irie, Kazuhiro; Tsukano, Chihiro (2021-08) European Journal of Organic Chemistry, 2021(30): 4269-4272 | |
Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin. Irie, Kazuhiro; Yanagita, Ryo C (2014-04) The Chemical Record, 14(2): 251-267 | |
Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities. Hanaki, Yusuke; Yanagita, Ryo C; Sugahara, Takahiro; Aida, Misako; Tokuda, Harukuni; Suzuki, Nobutaka; Irie, Kazuhiro (2015) Bioscience, biotechnology, and biochemistry, 79(6): 888-895 | |
Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin NAKAGAWA, Yu; KIKUMORI, Masayuki; YANAGITA, Ryo C.; MURAKAMI, Akira; TOKUDA, Harukuni; NAGAI, Hiroshi; IRIE, Kazuhiro (2011-06) Bioscience, Biotechnology, and Biochemistry, 75(6): 1167-1173 | |
Synthesis and characterization of the amyloid β40 dimer model with a linker at position 30 adjacent to the intermolecular β-sheet region. Murakami, Kazuma; Suzuki, Takashi; Hanaki, Mizuho; Monobe, Yoko; Akagi, Ken-Ichi; Irie, Kazuhiro (2015-10-23) Biochemical and biophysical research communications, 466(3): 463-467 | |
Synthesis and structure–activity studies of simplified analogues of aplysiatoxin with antiproliferative activity like bryostatin-1 Irie, Kazuhiro; Kikumori, Masayuki; Kamachi, Hiroaki; Tanaka, Keisuke; Murakami, Akira; Yanagita, Ryo C.; Tokuda, Harukuni; Suzuki, Nobutaka; Nagai, Hiroshi; Suenaga, Kiyotake; Nakagawa, Yu (2012) Pure and Applied Chemistry, 84(6): 1341-1351 | |
Synthesis of Alkyl Bridged‐Tris‐α‐Amino Acids as C₃‐Symmetric and Linear Linkers Uchino, Ayumi; Tsukano, Chihiro; Imamoto, Tsuneo; Irie, Kazuhiro (2021-03-05) European Journal of Organic Chemistry, 2021(9): 1370-1377 | |
Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology Murakami, Kazuma; Kato, Haruka; Hanaki, Mizuho; Monobe, Yoko; Akagi, Ken-ichi; Kawase, Taiji; Hirose, Kenji; Irie, Kazuhiro (2020) RSC Advances, 10(33): 19506-19512 |